Which ions are moved in the "321 NOKIA" mnemonic related to the sodium-potassium pump?

Which ions are moved in the "321 NOKIA" mnemonic related to the sodium-potassium pump?

• A. 3 K in, 2 Na out
• B. 2 K in, 3 Na out
• C. 1 Ca in, 2 Na out
• D. 2 Ca out, 3 Na in

Answer: (B)

The correct answer is based on the fundamental mechanics of the sodium-potassium pump (Na+/K+ ATPase), which is crucial for maintaining the electrochemical gradient across the plasma membrane of cells. The "321 NOKIA" mnemonic serves as a helpful tool to remember the behavior of this pump. In the case of the sodium-potassium pump, it actively transports three sodium ions (Na+) out of the cell and two potassium ions (K+) into the cell for each cycle of the pump. This movement is vital for various cellular processes, such as nerve impulse transmission and muscle contraction. The ratio of three sodium ions expelled and two potassium ions imported helps establish a more positive charge outside the cell compared to the inside, contributing to the resting membrane potential that is essential for cellular excitability. The mnemonic emphasizes this sequence by breaking it down into memorable numbers and context, specifically relating to the brands of mobile phones to aid retention. By grasping the "321" aspect, one can clearly recall that the pump's operation is three Na+ ions exiting the cell while two K+ ions are brought in, reinforcing the idea that option describing two K+ in and three Na+ out is the correct representation of this physiological mechanism.

The correct answer is based on the fundamental mechanics of the sodium-potassium pump (Na+/K+ ATPase), which is crucial for maintaining the electrochemical gradient across the plasma membrane of cells. The "321 NOKIA" mnemonic serves as a helpful tool to remember the behavior of this pump.

In the case of the sodium-potassium pump, it actively transports three sodium ions (Na+) out of the cell and two potassium ions (K+) into the cell for each cycle of the pump. This movement is vital for various cellular processes, such as nerve impulse transmission and muscle contraction. The ratio of three sodium ions expelled and two potassium ions imported helps establish a more positive charge outside the cell compared to the inside, contributing to the resting membrane potential that is essential for cellular excitability.

The mnemonic emphasizes this sequence by breaking it down into memorable numbers and context, specifically relating to the brands of mobile phones to aid retention. By grasping the "321" aspect, one can clearly recall that the pump's operation is three Na+ ions exiting the cell while two K+ ions are brought in, reinforcing the idea that option describing two K+ in and three Na+ out is the correct representation of this physiological mechanism.